Conclusion  Genetic variation in CYP2A6 does not appear to be an important determinant of dexmedetomidine clearance in ICU patients.




Content Type Journal ArticleCategory PharmacogeneticsPages 1-6DOI 10.1007/s00228-011-1208-zAuthors
Utkarsh Kohli, Departments of Medicine and Pharmacology, Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USAPratik Pandharipande, Division of Critical Care Medicine, Department of Anaesthesiology, Vanderbilt University, Nashville, TN, USAMordechai Muszkat, Departments of Medicine and Pharmacology, Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USAGbenga G. Sofowora, Departments of Medicine and Pharmacology, Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USAEitan A. ...

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