Hyperactivity Information Thread, Cathechol-O-methyltransferase Val158Met polymorphism is associated with disruptive behavior disorders among children and adolescents with ADHD in H; Abstract
COMT Val
158
Met polymorphism has been associated with both symptoms of attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior
disorders ...
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February 7th, 2012, 8:54 PM
#1
Cathechol-O-methyltransferase Val158Met polymorphism is associated with disruptive behavior disorders among children and adolescents with ADHD
Abstract
COMT Val
158
Met polymorphism has been associated with both symptoms of attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior
disorders (DBD): that is, oppositional defiant disorder (ODD) and conduct disorder (CD) often comorbid with ADHD. The aim
of this study was to test the association between COMT Val
158
Met polymorphism and the presence of DBD in children with ADHD (n = 516). Homozygous Val/Val children showed a higher prevalence of ADHD comorbid with DBD (
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