Hyperactivity Information Thread, Importance of Pharmacokinetic Profile and Timing of Coadministration of Short- and Long-Acting Formulations of Methylphenidate on Patterns of Subjective Responses and Abuse Potential in H; Conclusion: These results emphasize the critical role that formulation type (IR vs OROS) and timing of administration (ascending vs descending ...
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February 9th, 2012, 9:10 PM
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Importance of Pharmacokinetic Profile and Timing of Coadministration of Short- and Long-Acting Formulations of Methylphenidate on Patterns of Subjective Responses and Abuse Potential
Conclusion: These results emphasize the critical role that formulation type (IR vs OROS) and timing of administration (ascending vs descending phase) play when short- and long-acting formulations are coadministered. Such knowledge provides important information for clinicians about the safety and tolerability of the timing of repeat dosing of various permutations of coadministration of MPH formulations.
Keywords: stimulants; drug abuse liability; attention-deficit/hyperactivity disorder
read more (Source: Postgraduate Medicine Online)
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