Duloxetine hydrochloride

[Blue]

Duloxetine hydrochloride (brand names: Cymbalta/Yentreve and in parts of Europe known as Xeristar or Ariclaim) is a drug that primarily targets Major depressive disorder (MDD), Generalized Anxiety Disorder (GAD), pain related to diabetic peripheral neuropathy and in some countries stress urinary incontinence (SUI). Duloxetine has not not been FDA approved for SUI or for fibromyalgia. It is manufactured and marketed by Eli Lilly and Company. Cymbalta for MDD was considered safe and well tolerated in a 52-week open-label study of 1,279 patients., although the manufacturer states that the effectiveness of Cymbalta in long-term use for MDD for more than 9 weeks has not been systematically evaluated in controlled trials.
Duloxetine is labeled an SNRI for serotonin norepinephrine reuptake inhibitor. Duloxetine is a systemic drug therapy that affects the body as a whole. Known also under the code name LY248686, it is a potent dual reuptake inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE), possessing comparable affinities in binding to NE- and 5-HT transporter sites. It is a less potent inhibitor of dopamine reuptake.

More Info, Source and Links:
http://en.wikipedia.org/wiki/Duloxetine

[CrazyDog]

Cymbalta has seemed to be effective for my depression, at least for now. Have been on most of the ssri's and effexor, but now take Cymbalta and Remeron. Hopefully this combo will continue to be effective.

[Blue]

Nice to know it is working to a degree, have you been diagnosed with any specific form of depression?

[CrazyDog]

Ihave been dx'd with mdd for several years now. I have tried almost all of the ssri's and also effexor and 1 tca.

[Blue]

What is MDD? And have you ever seen a Pychiatrist or is your medication prescribed by a normal doctor??

[CrazyDog]

Sorry, MDD stands for Major Depressive Disorder, and yes I see a pdoc (psychiatrist).