Source: NHS Evidence
Area: News
The February edition of 'Eyes on Evidence', the free monthly e-bulletin from NHS Evidence covering major new evidence with an explanation about what it means for current practice, includes an expert commentary on new evidence from a large single centre cohort study which examined the clinical impact of staggered overdoses and delayed presentation following paracetamol overdose.
 
The study analysed data from 663 patients who were admitted for paracetamol-induced liver injury, of whom 161 (24.3%) had taken a staggered overdose, usually to relieve a variety of common pains, such as abdominal or muscular pains, headache and toothache.
 
The researchers suggest that prognostic criteria may have reduced sensitivity in staggered overdose patient...

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