Postnatal Depression Information Thread, Use of dosulepin in pregnancy in P; Source: UK Teratology Information Service
Area: Evidence > Drugs in Pregnancy
SUMMARY: Dosulepin (formerly known as dothiepin) is a tricyclic ...
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February 7th, 2012, 8:54 PM
#1
Use of dosulepin in pregnancy
Source: UK Teratology Information Service
Area: Evidence > Drugs in Pregnancy
SUMMARY: Dosulepin (formerly known as dothiepin) is a tricyclic antidepressant used in the treatment of depression, particularly where sedation is required.
There is very little published data regarding the use of dosulepin in pregnancy. Neonatal withdrawal symptoms may occur following chronic use or use near the time of delivery of any antidepressant. The neonate should be monitored for adverse effects such as drowsiness, jitteriness, hyperexcitability and suckling problems. Some studies have suggested that exposure to tricyclic antidepressants (TCAs) and other antidepressants in pregnancy may be associated with an increased risk of spontaneous abortion, low birth weight and IUGR.&...
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